Anti-autoimmune effect of the parasites: the microbial immunomodulation

Parasites with their ability to vibrate our immune system are known as potent immunomodulators. In the course of life struggle of parasites within host body, they induce our immune system to produce immunosuppressive cytokines like IL-4 and IL-10 by the immune cells to create parasite friendly environment within host body. Coincidentally, several autoimmune and inflammatory disorders of the host body, if existed get also relax from self aggression of the immune cells. Various recent reports have proven the relieving effects of parasitic infection among the people suffering from discriminative failure of the immune system between self and non-self. Few of those reports, on the basis of their detailed mechanism of action are critically reviewed in the present article to find out if they can be clinically employed for the treatment of billions of people across the world suffering from immune aggression.